Press Releases May 26, 2026 08:00 AM

Annovis Bio Regains NYSE Listing Compliance

Annovis Bio Regains NYSE Listing Compliance Ahead of Deadline, Focuses on Advancing Phase 3 Trials for Neurodegenerative Diseases

By Hana Yamamoto
Share
Twitter Reddit Facebook LinkedIn
ANVS

Annovis Bio, Inc., a clinical-stage biotechnology company focused on treatments for Alzheimer's and Parkinson's diseases, has regained compliance with NYSE listing standards after executing corrective actions to restore market capitalization and stockholders' equity above required thresholds. The company is now focusing on advancing its Phase 3 clinical programs and upcoming regulatory submissions for its lead drug candidate, buntanetap.

Annovis Bio Regains NYSE Listing Compliance
ANVS
Summarize with
ChatGPT Perplexity Claude Grok Gemini

Key Points

  • Annovis Bio regained full compliance with NYSE continued listing standards well ahead of the 18-month cure period deadline.
  • The company's lead drug candidate, buntanetap, is a Phase 3 oral therapy being developed for neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
  • With listing concerns resolved, the company plans to focus on clinical milestones including top-line data from the pivotal Phase 3 Alzheimer's study and upcoming regulatory submissions.

MALVERN, Pa., May 26, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), announced today that it has regained compliance with the New York Stock Exchange (NYSE) continued listing standards.

On March 26, 2025, the NYSE notified Annovis of its non-compliance with Section 802.01B of the NYSE Listed Company Manual, as the Company's average global market capitalization had fallen below $50 million over a consecutive 30-trading-day period while its stockholders' equity was also below $50 million. On June 19, 2025, the NYSE accepted the Company's plan to regain compliance and granted an 18-month cure period from the date of the original notice.

To address it, Annovis executed a series of corrective actions to restore its market capitalization and stockholders' equity above the required thresholds and provided the NYSE with quarterly progress updates as required under the plan. Following these measures, the NYSE has confirmed that Annovis has regained full compliance with all applicable continued listing requirements. The Company's common stock will continue to be listed and traded on the NYSE under the ticker symbol "ANVS."

"We are pleased to have regained full NYSE compliance in just 12 months, well ahead of the 18-month deadline, and we thank the NYSE for their engagement throughout this process," said Alexander Morin, Ph.D., Director, Strategic Communications. "With this matter behind us, our attention remains firmly on advancing our clinical programs toward key milestones, with topline data readout from the pivotal Phase 3 AD study and the regulatory submissions on the horizon."

About Annovis
Headquartered in Malvern, Pennsylvania, Annovis Bio, Inc. (NYSE: ANVS) is a Phase 3 clinical-stage biotechnology company developing treatments for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The Company's lead drug candidate, buntanetap (formerly posiphen), is an investigational once-daily oral therapy that inhibits the translation of multiple neurotoxic proteins, including APP and amyloid beta, tau, alpha-synuclein, and TDP-43, through a specific RNA-targeting mechanism of action. By addressing the underlying causes of neurodegeneration, Annovis aims to halt disease progression and improve cognitive and motor functions in patients. For more information, visit www.annovisbio.com and follow us on LinkedIn, YouTube, and X.

Investor Alerts
Interested investors and shareholders are encouraged to sign up for press releases and industry updates by registering for email alerts at https://www.annovisbio.com/email-alerts.

Forward-Looking Statements
This press release contains forward-looking statements under the Securities Act of 1933 and the Securities Exchange Act of 1934, as amended. Actual results may differ due to various risks and uncertainties, including those outlined in the Company’s SEC filings under “Risk Factors” in its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no obligation to update forward-looking statements except as required by law.

Contact Information:
Annovis Bio Inc.
101 Lindenwood Drive
Suite 225
Malvern, PA 19355
www.annovisbio.com

Investor Contact:
Alexander Morin, Ph.D.
Director, Strategic Communications
Annovis Bio
ir@annovisbio.com


Risks

  • Previous non-compliance with NYSE standards reflects underlying challenges with market capitalization and equity levels that could recur.
  • Clinical development risks associated with Phase 3 trials of buntanetap, including potential for trial failure or delays, which would impact financial and operational outlook.
  • Regulatory risks inherent in the drug approval process, which may affect the timing and success of market entry, impacting shareholder value.

More from Press Releases

Nuwellis Announces Closing of $6.0 Million Registered Public Offering Jun 8, 2026 Grupo Aeroportuario del Pacifico Publishes its 2025 Sustainability Report Jun 8, 2026 Cipher Digital Inc. Announces Pricing of $810.0 Million of Senior Secured Notes Jun 8, 2026 Ocean Capital Acquisition Corporation Prices $100 Million Initial Public Offering Jun 8, 2026 Cibus Names Agricultural Biotechnology Leader Craig Wichner as Chief Executive Officer to Accelerate Growth and Value Creation Jun 8, 2026