Insider Trading April 17, 2026 05:24 PM

United Therapeutics CEO Executes $5.48M Stock Sale, Exercises Options Under 10b5-1 Plan

Martine Rothblatt sold shares across several trades and exercised options the same day; analysts have raised price targets amid encouraging trial data

By Ajmal Hussain UTHR
United Therapeutics CEO Executes $5.48M Stock Sale, Exercises Options Under 10b5-1 Plan
UTHR

Martine Rothblatt, chairperson and CEO of United Therapeutics Corp (NASDAQ: UTHR), sold $5.48 million of company stock on April 16, 2026, in multiple transactions at prices between $573.9595 and $581.3325. On the same day she exercised options to acquire 9,500 shares at $146.03 per share. The trades were carried out under a 10b5-1 plan adopted November 7, 2025. Several analysts have recently lifted price targets for United Therapeutics following trial data and regulatory designations for the company’s programs.

Key Points

  • Martine Rothblatt sold $5.48 million of United Therapeutics stock on April 16, 2026, across multiple transactions at prices between $573.9595 and $581.3325.
  • Rothblatt also exercised options to acquire 9,500 shares at $146.03 on April 16, 2026, for a total of $1,387,285.
  • Analysts have raised price targets for United Therapeutics after favorable trial data and regulatory developments, including Raymond James’ Outperform initiation with a $700 target and FDA RMAT designation for a subsidiary device.

Martine Rothblatt, who serves as chairperson and chief executive officer of United Therapeutics Corp (NASDAQ: UTHR), completed a set of stock sales on April 16, 2026, totaling $5.48 million. The disposition was executed in several tranches with sale prices ranging from $573.9595 to $581.3325 per share.

The detailed breakdown of the transactions is as follows:

  • 400 shares sold at $573.9595
  • 1,800 shares sold at $574.7892
  • 930 shares sold at $575.9883
  • 2,048 shares sold at $577.0326
  • 2,027 shares sold at $578.0501
  • 1,750 shares sold at $579.3649
  • 385 shares sold at $579.8397
  • 160 shares sold at $581.3325

In addition to the share sales, Rothblatt exercised stock options on the same date to acquire 9,500 shares at an exercise price of $146.03 per share, representing a total outlay of $1387285.

All of these transactions were carried out pursuant to a pre-arranged 10b5-1 trading plan adopted on November 7, 2025. According to the plan’s disclosure, it permits the exercise of 1,734,410 stock options that either expire on March 17, 2027, or remain exercisable until December 31, 2026.

Following the April 16 activity, Rothblatt’s direct ownership in United Therapeutics stands at 40,513 shares. Indirect holdings include 166 shares held by a spouse and blocks of shares held in trusts: 324,443; 258,117; 45,596; and 10,962, respectively.


United Therapeutics has also drawn notable analyst attention in recent days after reporting earnings and revenue results. Raymond James initiated coverage on the company with an Outperform rating and a price target of $700. That firm’s view includes an expectation that Tyvaso, indicated for the treatment of idiopathic pulmonary fibrosis (IPF), could reach more than $5 billion in peak sales.

Regulatory progress for a subsidiary program was also highlighted. The U.S. Food and Drug Administration granted Regenerative Medicine Advanced Therapy designation to miroliverELAP, an investigational liver assist device developed by United Therapeutics’ subsidiary Miromatrix Medical Inc.

Following recent trial data, multiple brokerages adjusted their price targets for United Therapeutics. H.C. Wainwright raised its target to $660 from $600 and maintained a Buy rating, citing promising results from the TETON-1 trial for Tyvaso in IPF. BofA Securities lifted its price target to $626 from $569, noting favorable Phase 3 TETON-1 trial data. Jefferies increased its price target to $733 from $668, and revised its estimated probabilities of success for Tyvaso to 95% in IPF and 70% in progressive pulmonary fibrosis.

Taken together, the insider transactions and the raft of analyst updates mark a busy period for United Therapeutics, combining executive portfolio adjustments with intensified market scrutiny of the company’s therapeutic prospects.

Risks

  • Insider sales may be perceived by some investors as a reduction in insider-held shares; the sales occurred under a pre-arranged 10b5-1 plan adopted on November 7, 2025 - this affects investor interpretation in the equity markets and healthcare sector.
  • The 10b5-1 plan permits exercise of 1,734,410 options expiring on March 17, 2027, or until December 31, 2026, which could result in future share issuance and potential dilution impacting United Therapeutics’ stock in the broader healthcare and biotech markets.
  • Analyst price target revisions are predicated on trial data and regulatory actions; changes in trial outcomes or regulatory decisions could alter market expectations for Tyvaso and related programs, influencing biotech sector valuations.

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