Stock Markets April 21, 2026 10:32 AM

Stocks With Big Moves Tuesday: UnitedHealth, Avis Among Winners; Eli Lilly, Tractor Supply Slip

Healthcare, consumer discretionary and industrials see notable swings as earnings, guidance and corporate actions drive midweek trading

By Leila Farooq UNH INTC LLY CAR
Stocks With Big Moves Tuesday: UnitedHealth, Avis Among Winners; Eli Lilly, Tractor Supply Slip
UNH INTC LLY CAR

Trading on Tuesday produced wide swings across market-cap ranges. UnitedHealth surged after new rural hospital support programs were highlighted, Avis Budget led gains among large-caps, and several mid- and small-cap names jumped on earnings beats or corporate developments. Eli Lilly and Tractor Supply were among the larger decliners.

Key Points

  • Healthcare and pharmaceuticals delivered large headline moves with UnitedHealth rallying and Eli Lilly sliding, affecting mega-cap sector performance.
  • Consumer discretionary and housing-related names showed strength on earnings beats and corporate developments, with Avis Budget and D.R. Horton among notable gainers.
  • Mid- and small-cap activity was driven by earnings, raised guidance and company-specific operational updates, including Vaalco's initial Gabon well production and Aeluma's NASA award.

U.S. equity markets on Tuesday registered sizable moves from large-cap names down through small-caps as company-specific news and analyst activity drove volatile session-to-session shifts. Below is a company-by-company breakdown of the most pronounced gainers and decliners across market-cap categories, with the specific percentage moves and the company explanations noted in reports and filings.


Mega-Cap Movers ($200 billion USD or higher)

  • UnitedHealth Group (UNH) - UnitedHealthcare expanded rural hospital support programs, and the stock rallied +9.75%.
  • Intel Corp (INTC) - HSBC upgraded Intel's stock rating on a brighter server CPU growth outlook, sending the shares up +1.64%.
  • Eli Lilly And Co (LLY) - Shares declined -2.52%.

Large-Cap Stock Movers ($10-$200 billion USD)

  • Avis Budget (CAR) - Shares surged +16.3%.
  • Astera Labs (ALAB) - UBS initiated coverage at neutral, citing competition in switching, and the stock rose +9.99%.
  • D.R. Horton Inc (DHI) - D.R. Horton shares rose after reporting Q1 earnings and revenue that beat expectations, up +8.21% (the company noted a roughly 2% rise in the session).
  • Mueller Industries Inc (MLI) - The stock climbed +8.44%.
  • Quest Diagnostics (DGX) - Quest reported an earnings beat and raised guidance, and its stock rose +4.26%.
  • MSCI Inc (MSCI) - MSCI beat Q1 estimates but delivered muted guidance, and the shares gained +5.9%.
  • Moderna (MRNA) - The European Commission approved Moderna's flu-COVID combination vaccine, and the stock moved up +2.12%.
  • Toll Brothers (TOL) - Shares increased +2.83%.
  • Tractor Supply Company (TSCO) - Tractor Supply fell after an earnings report that missed analyst estimates, down -8.45%.
  • Prudential Fin (PRU) - The stock declined -4.57%.

Mid-Cap Stock Movers ($2-$10 billion USD)

  • Live Oak Acq (NVTS) - The shares jumped +22.84%.
  • Valmont Industries Inc (VMI) - Valmont rose after an earnings beat and raised guidance, moving +14.42%.
  • York Space Systems Inc (YSS) - The stock gained +10.8%.
  • MaxLinear Inc (MXL) - Shares increased +7.91%.
  • Robert Half Intl (RHI) - The shares were up +5.89%.
  • Arcus Biosciences Inc (RCUS) - The stock rose +4.22%.
  • AXT Inc (AXTI) - AXT announced a planned public stock offering to expand production capacity and the shares fell -4.55%.
  • Oaktree Acquisition Corp (HIMS) - Shares slipped -1.64%.
  • CF Acquisition Corp VI (RUMBW) - The stock fell -10.46%.
  • Puyi ADR (MAAS) - The ADR declined -15.76%.

Small-Cap Stock Movers ($300 million - $2 billion USD)

  • Velo3D (VELO) - The stock advanced +26.48%.
  • POET Tech NAQ (POET) - Shares climbed +19.03%.
  • Vaalco Energy Inc (EGY) - Vaalco reported initial production of 4,850 barrels of oil per day from a Gabon well and the stock rose +12.8%.
  • Pitney Bowes Inc (PBI) - Shares increased +11.49%.
  • Aevex Inc (AVEX) - The stock gained +13.11%.
  • Groupon Inc (GRPN) - Shares rose +13.11%.
  • Aeluma (ALMU) - Aeluma received a NASA award for quantum dot laser development and the stock moved up +7.98%.
  • AAOX (AAOX) - The shares were down -2.87%.
  • Washington Trust (WASH) - The stock fell -13.55%.

These moves spanned the market-cap spectrum and reflected a mix of corporate announcements, earnings results and analyst actions. The list above captures the largest percentage changes and the reasons reported alongside those moves where specified by company statements, regulatory notices or analyst commentary.

Risks

  • Earnings misses and analyst downgrades can materially weigh on individual company shares - example: Tractor Supply fell after an earnings miss, impacting the consumer retail sector.
  • Corporate actions such as planned stock offerings may exert downward pressure on share prices - AXT's announced public offering coincided with a share decline, affecting industrials and materials names.
  • Companies delivering muted or cautious guidance following quarterly beats may face investor scrutiny - MSCI beat Q1 estimates but provided muted guidance, introducing uncertainty for the financials and data-services segment.

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