Stock Markets January 23, 2026

Novo Nordisk's Oral Wegovy Launch Sees Strong Uptake in U.S. Market

New pill amplifies competition in obesity treatment as Novo Nordisk seeks to maintain lead over rivals

By Maya Rios NVO LLY
Novo Nordisk's Oral Wegovy Launch Sees Strong Uptake in U.S. Market
NVO LLY

Novo Nordisk’s recently introduced oral version of its weight-loss drug Wegovy garnered 18,410 prescriptions across the U.S. during its initial full week of availability. This promising start positions the Danish pharmaceutical firm to leverage its early mover advantage against competitors in the expanding obesity treatment segment. The prescription rate notably outpaces other glucagon-like peptide-1 (GLP-1) drug launches, indicative of growing patient preference for oral administration options. Market analysts track these developments closely as they signal shifts in patient adoption and competitive dynamics.

Key Points

  • Novo Nordisk’s oral Wegovy pill recorded 18,410 U.S. prescriptions in its first full week after launch, indicating strong early market acceptance.
  • Oral obesity treatments provide patients with a needle-free alternative, complementing existing injectables that continue to dominate the market.
  • Novo Nordisk is aiming to regain market momentum following previous sales challenges, supported by increasing investor confidence and CEO-led strategic initiatives.

Novo Nordisk, the Danish pharmaceutical company, made a strong entry into the oral obesity drug market with its recent introduction of the Wegovy pill. Analysts, relying on IQVIA data, report that during the first full week following its January 5 launch, the medication was prescribed 18,410 times across the United States. In the four days immediately following its launch, prescriptions totaled 3,071, marking a robust uptake early in its market presence.

This debut is particularly encouraging within the competitive weight-loss pharmaceutical arena, where investors and stakeholders closely monitor prescription trends to assess how effectively Novo Nordisk leverages its position against significant rivals such as Eli Lilly. The prescriptive adoption rate for the oral Wegovy pill reportedly surpasses early launch performance of comparable GLP-1 receptor agonist drugs.

Oral treatments for obesity, such as Wegovy's new pill form, provide patients with greater convenience and an alternative to the traditionally injected therapies that currently dominate the market. Despite this growing oral segment, injectable medications remain anticipated to hold a substantial market share for the foreseeable future. Barclays analyst James Gordon noted that the oral Wegovy's launch performance is notably strong, albeit within a market that is now more established in obesity care compared to earlier periods when such treatments were emerging.

Novo Nordisk’s strategic emphasis on the pill formulation aims to attract a wider patient base and rejuvenate growth momentum following challenges the company faced in the preceding year, which included profit warnings and slowing sales growth. Their shares have demonstrated a steady increase since the start of the calendar year, rising approximately 25% in January and reaching their highest valuation since late July concurrent with the leadership transition to CEO Mike Doustdar.

Meanwhile, the U.S. Food and Drug Administration is anticipated to issue a decision on Eli Lilly’s experimental oral obesity treatment, orforglipron, by April. Jefferies analyst Akash Tewari views the successful initial uptake of Novo Nordisk’s oral Wegovy as a favorable indicator for Lilly’s forthcoming product, anticipating its use primarily by patients inclined towards oral therapies rather than injectables.

Supporting the favorable launch trends, Guggenheim analysts have observed increased Google search interest in January for Novo Nordisk’s NovoCare Pharmacy and Wegovy. This search activity has exceeded that for LillyDirect, Lilly's own consumer engagement platform launched this month. Although searches related to tirzepatide, Lilly’s Zepbound injection, remain the highest within the obesity treatment category, growing online interest has also been noted for telehealth providers linked with Novo Nordisk, including Ro, LifeMD, and Hims & Hers.

Risks

  • Potential competitive pressure from Eli Lilly’s forthcoming oral obesity drug, pending FDA approval expected in April, could impact Novo Nordisk’s market share.
  • Despite early success, the obesity treatment market remains highly competitive with established injectable therapies maintaining significant patient and provider preference.
  • Market response to newer oral obesity treatments is still evolving, and sustained growth depends on continued patient adoption and reimbursement conditions.

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