Press Releases April 2, 2026

Spyre Therapeutics Announces Grants of Inducement Awards

Spyre Therapeutics Grants Stock Options to New Employees Under Equity Inducement Plan

By Ajmal Hussain SYRE
Spyre Therapeutics Announces Grants of Inducement Awards
SYRE

Spyre Therapeutics has granted stock options totaling 70,200 shares to five newly hired non-executive employees as inducement awards. The options have a 10-year term, an exercise price of $48.90 per share, and will vest over four years. This move aims to attract talent and support the company's ongoing clinical development of long-acting antibody therapies for inflammatory bowel disease and rheumatic diseases.

Key Points

  • Spyre granted 70,200 stock options to five new non-executive employees to incentivize recruitment.
  • Options granted have a 10-year term with an exercise price equal to the closing market price on April 1, 2026 ($48.90).
  • The company is advancing clinical-stage therapies targeting chronic inflammatory and rheumatic conditions such as IBD.
  • Sectors impacted include biotechnology, pharmaceuticals, healthcare, and equity capital markets.

WALTHAM, Mass., April 03, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase an aggregate of 70,200 shares of common stock of Spyre to five non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options were approved on April 1, 2026 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).

The stock options were granted with a 10-year term and an exercise price equal to $48.90, the closing price per share of Spyre's common stock as reported by Nasdaq on April 1, 2026. The options granted to the employees shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The stock options are subject to the terms of the 2018 Plan.

About Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.

For more information, please visit http://spyre.com.

For Investors :     
Eric McIntyre
SVP of Finance and Investor Relations
Spyre Therapeutics
Eric.mcintyre@spyre.com


Risks

  • The vesting of options is contingent upon continuous employment, which could impact retention and talent stability.
  • Market price volatility could affect the attractiveness and financial implications of the stock options.
  • Clinical-stage biotech companies like Spyre face inherent risks including clinical trial outcomes, regulatory approval, and commercialization challenges.

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