Insider Trading January 22, 2026

Precision Biosciences' Chief Research Officer Executes Share Sale Amid Notable Gene Editing Progress

Smith J. Jefferson sells shares while company advances clinical trials and strengthens cash reserves

By Sofia Navarro DTIL
Precision Biosciences' Chief Research Officer Executes Share Sale Amid Notable Gene Editing Progress
DTIL

Precision Biosciences Inc's Chief Research Officer, Smith J. Jefferson, recently sold over 10,000 shares of the company's stock while concurrently acquiring a larger number of shares from vested Restricted Stock Units. The company continues to move forward with key gene editing clinical trials and maintains strong liquidity after a recent capital raise, positioning itself well for upcoming data milestones.

Key Points

  • Chief Research Officer Smith J. Jefferson completed a sale of 10,200 shares at $4.03 each, totaling over $41,000, while also acquiring 29,166 shares via vested Restricted Stock Units.
  • Precision Biosciences is actively progressing its Phase 1/2a ELIMINATE-B trial for chronic hepatitis B and expects regulatory clearance for its Duchenne muscular dystrophy program in early 2026.
  • The company holds approximately $137 million in cash and equivalents as of the end of 2025, with funds from a recent $75 million equity offering expected to support milestones through 2028.

On January 21, 2026, Smith J. Jefferson, serving as Chief Research Officer for Precision Biosciences Inc (NASDAQ:DTIL), sold 10,200 shares of the company's common stock at $4.03 per share. This transaction amounted to approximately $41,106 in total proceeds.

Adding to his equity position, Jefferson received 29,166 shares through the vesting of Restricted Stock Units on January 20 and 21, 2026. These acquisitions reflect standard compensation practices aligning management interests with shareholder value.

Meanwhile, Precision Biosciences has announced continued advancements in its gene editing initiatives. The firm's Phase 1/2a ELIMINATE-B clinical trial, targeting chronic hepatitis B, is actively progressing, demonstrating early promise. Additionally, the company anticipates receiving regulatory approval for its Duchenne muscular dystrophy program during the first quarter of 2026, signaling potential pipeline expansion.

Financially, Precision Biosciences reported approximately $137 million in cash, cash equivalents, and restricted cash as of December 31, 2025. This funding is expected to support the company's data-driven milestones through 2028, reflecting prudent financial planning and resource allocation.

Further bolstering its balance sheet, the company recently completed an underwritten offering raising nearly $75 million by selling 10,815,000 shares of common stock along with attached warrants. This capital injection aims to fund ongoing research and development efforts.

Promising early-stage clinical data were also disclosed, highlighting results from the Phase 1 ELIMINATE-B study. The trial showed dose-dependent antiviral activity in all nine patients treated in the initial cohorts, underscoring the potential therapeutic benefits of Precision Biosciences’ gene editing approach for chronic Hepatitis B.

Collectively, these developments indicate the company’s sustained commitment to advancing innovative therapies within the gene editing sector, with financial strategies aligned to support long-term clinical progress.

Risks

  • Clinical trials remain ongoing, which inherently possess uncertainties related to safety, efficacy, and regulatory approval timelines, potentially impacting future performance.
  • While the company maintains substantial cash reserves, future capital requirements or market conditions could affect funding availability, influencing research and development capabilities.
  • The success of gene editing programs depends on complex scientific and regulatory factors; adverse results or delays could weigh on company valuation and investor sentiment.

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