Insider Trading January 22, 2026

Natera's President John Fesko Executes $4.26 Million Stock Sale Amid Encouraging Company Momentum

Stock sale aligned with tax obligations; company posts robust Q4 growth and advances in cancer detection technologies

By Priya Menon NTRA
Natera's President John Fesko Executes $4.26 Million Stock Sale Amid Encouraging Company Momentum
NTRA

John Fesko, serving as President and Chief Business Officer of Natera, Inc., recently completed the sale of over 18,000 shares of the company's stock, raising approximately $4.26 million. These transactions were part of a prearranged plan intended to meet tax liabilities related to vested equity awards. Concurrently, Natera reported strong preliminary fourth-quarter performance including significant revenue growth and expanded test volumes, alongside continued innovation in cancer diagnostics and genetic screening trials.

Key Points

  • John Fesko, Natera's President and Chief Business Officer, sold 18,145 shares valued at approximately $4.26 million to meet tax liabilities associated with vested RSUs.
  • Natera reported strong preliminary Q4 results with nearly 40% year-over-year revenue growth and a 17% increase in test volumes, exceeding analyst expectations.
  • The company is advancing precision oncology efforts through a phase 3 clinical trial for colorectal cancer and the launch of an AI model to enhance cancer recurrence risk assessment via molecular residual disease (MRD) testing.

John Fesko, who holds the position of President and Chief Business Officer at Natera, Inc. (NASDAQ:NTRA), conducted the sale of 18,145 shares of the company27s common stock on January 20 and 21. The total value of these sales reached $4,259,416, with share prices spanning from $234.7384 to $235.00 during the transactions.

On January 20, Fesko sold 17,806 shares, after which he maintained direct ownership of 177,591 Natera shares. The following day, he sold an additional 339 shares, reducing his direct holdings slightly to 177,252 shares.

These equity disposals were undertaken to fulfill tax obligations arising from the vesting of Restricted Stock Units (RSUs). They took place under a strict pre-established trading plan, designed in compliance with SEC Rule 10b5-1(c), which allows insiders to set predetermined schedules for trading stock, helping to avoid accusations of trading on material nonpublic information.

Beyond insider transactions, Natera recently released promising preliminary financial results for the fourth quarter. The company anticipates near 40% year-over-year revenue growth, outperforming analyst projections. Additionally, it reported approximately a 17% increase in test volumes, underscoring expanding demand for its genetic testing services.

Following these encouraging results, Canaccord Genuity reaffirmed its Buy rating on Natera shares and set a price target of $285.00, indicating confidence in the company27s growth trajectory.

Natera also announced a partnership with Exelixis to embark on a pivotal phase 3 clinical trial targeting colorectal cancer patients. This study will utilize Natera27s Signatera test, which is designed to detect molecular residual disease (MRD) and enable precise patient enrollment based on MRD presence.

In parallel, the company introduced an innovative multi-modal artificial intelligence model aiming to improve cancer recurrence risk assessments via enhanced MRD detection, representing a major step forward in precision oncology diagnostics.

Natera further plans to share data from its EXPAND clinical trial related to fetal genetic screening at the upcoming Society for Maternal-Fetal Medicine conference, indicating ongoing commitment to advancing prenatal care technologies.

Moreover, a study published in JAMA Oncology highlighted the efficacy of the company27s Signatera test in detecting MRD in colorectal cancer patients. The research demonstrated that patients receiving postoperative celecoxib treatment showed improved survival outcomes when monitored with this test.

These developments cumulatively illustrate Natera27s strategic focus on expanding its portfolio of genetic testing and cancer assessment solutions, positioning the firm at the forefront of innovation within the biotechnology and healthcare sectors.

Risks

  • Insider stock sales could be perceived negatively by investors, potentially impacting stock sentiment in the short term.
  • Despite preliminary strong results, there remains inherent clinical and regulatory risk associated with ongoing trials and new diagnostic technologies.
  • Market acceptance and commercial scalability of new diagnostic products, including AI-driven models and prenatal tests, involve operational and adoption uncertainties.

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